Durability of Vaccine-Induced Immunity Against Tetanus and Diphtheria Toxins: A Cross-sectional Analysis

Durability of Vaccine-Induced Immunity Against Tetanus and Diphtheria Toxins: A Cross-sectional Analysis.

BACKGROUND Many adult immunization schedules recommend that tetanus and diphtheria vaccination be performed every 10 years. In light of current epidemiological trends of disease incidence and rates of vaccine-associated adverse events, the 10-year revaccination schedule has come into question. METHODS We performed cross-sectional analysis of serum antibody titers in 546 adult subjects stratif...

Mass immunity against diphtheria and tetanus in sorne urban and rural areas in Iran

Does BCG vaccine induced trained immunity provide cross-protection against COVID-19?

During the global COVID-19 pandemic, the rate of mortality and morbidity was fairly low in Pakistan compared to western countries. Bacille Calmette-Guerin (BCG) vaccination provides cross-protection for a broad range of related and unrelated pathogens. This protection is attributed to the recognition of broadly cross-reactive Pathogen-Associated Molecular Pattern (PAMPS) like molecules. We inve...

Comparative Studies on the Purification of Tetanus and Diphtheria Toxins.

Diphtheria toxin has been identified as a typical heat-coagulable protein (Eaton 1936 a, 1937; Pappenheimer 1937). If other toxins have chemical properties similar to diphtheria toxin, they might be isolated by similar methods. Using a gelatin hydrolysate medium, Pappenheimer and Johnson (1936, 1937) have produced diphtheria toxin which may be obtained in a relatively pure state by simple fract...

A model for developing countries of mass serological survey of children vaccinated against diphtheria and tetanus